P R.E S E N T S              .

Handbook Of LC-MS Bioanalysis

DATE: 2017-10-11  SIZE: 33.9 MB    DISKS: 4x 10 MB    PAGES: n/a

PUBLISHER: Wiley                             GENRE:

AUTHOR: Wenkui Li, Jie Zhang, Francis L. S. Tse

FORMAT: PDF   PROTECTION: DRM  EDITION: n/a

URL: https://is.gd/rQ7VwQ

LANGUAGE: English   ISBN: 9781118159248

: Consolidates the information LC-MS bioanalytical scientists need to analyz :
: small molecules and macromolecules The field of bioanalysis has advanced   :
: rapidly, propelled by new approaches for developing bioanalytical methods, :
: new liquid chromatographic (LC) techniques, and new mass spectrometric (MS :
: instruments. Moreover, there are a host of guidelines and regulations      :
: designed to ensure the quality of bioanalytical results. Presenting the    :
: best practices, experimental protocols, and the latest understanding of    :
: regulations, this book offers a comprehensive review of LC-MS bioanalysis  :
: of small molecules and macromolecules. It not only addresses the needs of  :
: bioanalytical scientists working on routine projects, but also explores    :
: advanced and emerging technologies such as high-resolution mass            :
: spectrometry and dried blood spot microsampling. Handbook of LC-MS         :
: Bioanalysis features contributions from an international team of leading   :
: bioanalytical scientists. Their contributions reflect a review of the      :
: latest findings, practices, and regulations as well as their own firsthand :
: analytical laboratory experience. The book thoroughly examines:            :
: Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and :
: therapeutic drug monitoring The current understanding of regulations       :
: governing LC-MS bioanalysis Best practices and detailed technical          :
: instructions for LC-MS bioanalysis method development, validation, and     :
: stability assessment of analyte(s) of interest Experimental guidelines and :
: protocols for quantitative LC-MS bioanalysis of challenging molecules,     :
: including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and  :
: photosensitive and autooxidative compounds With its focus on current       :
: bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytica :
: scientists to develop and validate robust LC-MS assay methods, all in      :
: compliance with current regulations and standards.                         :

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